Rapid mammalian cell-free expression

Glycosylated IgGs.
In hours.

Fynd Bio kits let antibody discovery teams move from sequence to physically testable, full-sized glycosylated IgG without waiting days for conventional cell-based expression. Choose a human HEK or CHO-derived mammalian system to match your discovery workflow.

For research use only. Expression performance depends on sequence and workflow conditions.

Illustration of a full-length antibody
<24 hourssequence-to-protein workflow
HEK or CHOglycosylated full-length IgGs
Built for discoveryScreen candidates before committing to conventional expression.
Human or CHO glycosylationChoose HEK-derived or CHO-derived mammalian expression biology.
Automation-readyFormats suited to parallel, high-throughput workflows.
Glycosylation options

Choose human HEK or CHO glycosylation.

Fynd Bio kits produce full-length, glycosylated IgGs in mammalian cell-free systems. Select a human HEK-derived or CHO-derived glycosylation environment according to your antibody discovery workflow.

Human HEKHuman-derived mammalian glycosylation environment.
CHOCHO-derived mammalian glycosylation environment.
How it works

Resolve the antibody expression bottleneck.

Bring rapid physical validation closer to sequence design. Add DNA, run the reaction, and move promising candidates into binding or developability assays.

1

Add your DNA

Start with your antibody sequence in a compatible linear or plasmid template.

2

Run cell-free expression

Produce assembled, glycosylated antibody in a human HEK or CHO-derived cell-free environment without growing and transfecting intact cells.

3

Test and triage

Use the output to prioritize expression success, binding and early developability signals.

Experimental evidence

Real antibody output. Measured directly.

The platform has produced full-length trastuzumab IgG in mammalian cell-free reactions. Human HEK and CHO-derived systems provide a choice of mammalian glycosylation environment, while related cell-free workflows support rapid binding measurements from crude output.

SDS-PAGE gel showing antibody expression

Full-length, glycosylated IgG expression

Choose a human HEK or CHO-derived system. Non-reducing and reducing SDS-PAGE workflows provide direct confirmation of assembled IgG and heavy/light chains.

Binding sensorgram from cell-free expressed antibody

Functional binding readout

Cell-free-produced binders can move rapidly into affinity testing, including measurements from crude reaction material.

Applications

Make more antibody decisions, sooner.

AI-designed antibody screening

Close the design–build–test loop faster and generate more useful wet-lab feedback for model improvement.

Glycosylation-aware screening

Evaluate full-length IgGs in either a human HEK or CHO-derived glycosylation environment before committing to conventional production.

Sequence-to-binding services

Move from a digital sequence to expression and binding data through a streamlined service workflow.

Alternative antibody formats

Custom workflows for nanobodies, VHs, scFvs, HCAbs, DARPins, minibinders and other formats.

Stop waiting days to test an antibody.

Tell us the antibody format, throughput, assay and preferred glycosylation environment. We’ll recommend a human HEK or CHO-derived kit or service workflow for your discovery program.

Request information